Dr. Rhonda Patrick explains what antioxidants are, why they are important, and how they prevent DNA damage, a well-known cancer initiator, in order to minimize damage to DNA.
However, in the context of someone that already has cancer, DNA damage can activate genes that kill cancer cells. Dr. Patrick also reveals there are two major forms of vitamin E (alpha and gamma tocopherol) that have separate functions. Taking mega doses (i.e. 400 IU/day) of alpha tocopherol actually DEPLETES gamma tocopherol levels and has negative effects that may lead to prostate cancer.
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Source: Do Antioxidants Cause Cancer?